Natural Cycle Protocol

Is used when high dose gonadotropin injections are made and still no more than 1-2 follicle eggs are developed and to people with low over capacity.

The purpose is to protect from local procedure complications of gonadotropin and high costs. Just like in other protocols the treatment starts by looking for E2 in the blood on the 1^st, 2^nd and 3^rd day of the menstrual period and with transvaginal ultrasonography.

When the biggest follicle reaches 13-14 mm or when E2 is 100-200pg/ml daily, a single dose of 0.25 mg antagonist treatment and gonadotropin injection (150IU/day) starts. Daily antagonist injections including on the hCG day is ongoing. When at least 2 follicles bigger than 17mm are detected hCG is given and 36 hours later egg gathering process begins.

In the natural cycle, reaching the oocyte gathering stage 28.6-91%, reaching the embryo transfer 4-81% and 2-17% of pregnancy rate has been reported.